Use and safety of bisphosphonates in pediatric osteoporosis
ZHANG Hui-wen
JIANG Wen-jun
Abstract：Bisphosphonates are one of classical drugs in orthopaedics department used for prevention of bone resorption in adulthood.In recent years,bisphosphonates have been increasingly used in pediatric patients for the treatment of osteoporosis,and studies have shown the safety and effective result of BPs in increasing bone density and reduce the rate of fracture.However,considering adverse reactions of BPs in adult patients,the potential consequences in children still should be monitored.The current well-defined criteria for the use of BPs in pediatrics are still not clear,and the children will still need to be closely followed up.This review focused on the latest advances of bisphosphonate treatment in pediatric patients,introducing some of the clinical general measures and recommendations that have been reported,and discussing the common and potential adverse effects.
Keywords：bisphosphonateschildosteoporosisosteogenesis imperfecta
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 655-659 )