Talking about the fluid resuscitation in septic shock once again
GAO Heng-miao
Abstract：Fluid resuscitation continues to be recommended as the first-line resuscitative therapy for patients with septic shock.The current acceptance of the therapy is based in part on long history and familiarity with its use in the resuscitation of other forms of shock,as well as on an incomplete and incorrec.t understanding of the pathophysiology of septic shock.Recently,the safety of intravenous fluids resuscitation in patients with septic shock has been called into question with both prospective and observational data suggesting improved outcomes with less fluid.The current evidence for the continued use of fluid resuscitation for septic shock remains contentious with no prospective evidence demonstrating benefit to fluid resuscitation as a therapy in isolation.The article reviews the pathophysiological rationale for the introduction of fluid resuscitation as treatment for septic shock and highlights a number of significant concerns based on current clinical evidence.
Keywords：septic shockfluid resuscitationchild
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 425-430 )