Application of neuroimaging in pediatric brain cognitive function: Using functional magnetic resonance imaging to explore the cognitive neural mechanism of children with depression
Abstract：Functional magnetic resonance imaging (fMRI) is one of the most important technologies in pediatric brain cognitive function research;it is also an important method in the field of psycho-radiology which aims to study the abnormalities of neural basis in the patients with mental disorders.Pediatric depression is one of the most common mental disorders in children.It is thought frequently that the children with major depressive disorder (MDD) have their specific neural and physiological basis.Based on the findings from the task state fMRI studies,children with MDD demonstrated impairment in the cognitive,emotional and social cognitive functions.And the pediatric MDD shows alteration in the key brain areas involved in the cognitive,affective and rewared processing,including the amygdala,anterior cingulate,prefrontal and orbitofrontal cortex.The future research should consider the psychological development of children in the selection of the appropriate cognitive and affective task or paradigm to explore the brain function of the pediatric MDD.For children at high risk of depression,we should carry out systematic preventive research to provide experimental evidence for neuroimaging and psychological markers of early warning and for the development of early intervention methods.
Keywords：childmajor depressioncognitive taskpsycho radiology
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 289-293 )