Comparing the measurements of exhaled nitric oxide of the children from 3 to 5 years old during tidal breathing

doi:10.19538/j.ek2017030611

Abstract：Objective To compare the FeNO (Fractional exhaled nitric oxide,FeNO)of the children 3-5 years old by facemask with that by mouthpieces during tidal breathing,and to analyze the applicative value of the measurement for the children 3 to 5 years old.Methods From Junuary 2016 to August 2016,the children who came to Guangzhou Women's and Children's Medical Center to take the FeNO experiment were selected as the research subjects.During tidal breathing,children used the facemask to cover their nose and mouth to breath,or word the nose clip and used the mouthpieces to breath during the FeNO test.After the test,the clinical data were summarized and analyzed.Results The cases,which have no coughing and wheezing symptoms,whether with rhinitis or not,currently using the mouthpieces to measure the FeNO,were fewer than which using the facemask.The result of using mouthpieces and facemask to test in children with rhinitis was (7.8± 10.6) × 10-9 vs.(15.8±9.9) × 10-9 and,without rhinitis it was (5.0±4.5) × 10-9 vs.(14.0± 10.0) × 10-9 respectively,P ＜ 0.05.The children having coughing or wheezing symptoms,whether with rhinitis or not,using the mouthpieces to measure the FeNO,was fewer than those using the facemask.The result of using mouthpieces and facemask to test in children with rhinitis was 6.1×10-9[(2.1 ～ 16.3) ×10-9 vs.11.6×10-9[(4.1 ～26.5) ×10-9] and in those without rhinitis it was 4.6×10-9[(1.9 ～ 9.9) ×10-9] vs.11.5×10-9[(6.5 ～ 25.8) × 10-9] respectively,P ＜ 0.05.All of them were statistically different.Conclusion When we measure the FeNO in children from 3 to 5 years old during tidal breathing,breathing through the mouthpieces can reflect the airway inflammation better.