Detection for phenotype and genetype of the enterococci in children
LV Ping
XU Xi-wei
SONG Wen-qi
DONG Fang
YANG Yong-hong
SHEN Xu-zhuang
Abstract：Objective To detect the drug resistant phenotype and drug resistant genetype of the enterococci in children.Methods Agar dilution was used to study the drug resistance and polymerase chain reaction was used to test ermB,mefA, TetM, TEM, aac (6')-aph (2") and ant (6)-Ⅰ gene. Results The resistant rate of E.faecium toampicillin,amoxicillin-clavulanic acid, ciprofloxacin, rifampin, high level gentamicin and streptomycin were higher than E.faecalis.The resistant rate of E.faecium to chloramphenicol was higher than E.faecalis.The MIC of vancomycin was 8ug/ml in two E.faecalis.In E.faecalis and E.faecium isolates were all susceptible to teicoplanin.High rates of antibiotic resistance genes were found.The detectable rate of ermB, TetM aac (6')-aph (2") and ant (6)-Ⅰ gene in E.faecalis was higher than in E.faecium. In only one E.faecium was found MefA. The detecable rate of TEM in E.faecium was higher than in E.faecalis. Conclusions The antimicrobial resistant status of the enterococci is very serious.High rate of antibiotic resistance for multiple antibiotics were found in enterococci, the antibiotic resistante rate in E.faecium is higher than in E.faecalis.
Keywords：enterococciantobiotics antimicrobialantimicrobial resistance
Publication Date：2009-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 937-939 )