The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease

Mengyun Yue; Tingtao Chen; Wenjie Chen; Jing Wei; Bin Liao; Jie Zhang; Fangjun Li; Daojun Hong; Xin Fang

doi:10.4103/NRR.NRR-D-24-00702

🤖This page has been translated by AI and may contain inaccuracies. Please refer to the original content for clarification.

Home>Articles>The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease

DOI: 10.4103/NRR.NRR-D-24-00702

The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease

Mengyun Yue

Tingtao Chen

Wenjie Chen

Jing Wei

Bin Liao

Jie Zhang

Fangjun Li

Daojun Hong

Xin Fang

Keywords：A53T transgenic miceengineered probioticsglucagon-like peptide-1gut dysbacteriosisgut-brain axisLactococcus lactis MG1363-pMG36e-GLP-1microglial polarizationneurodegenerative diseaseneuroinflammationParkinson's disease

Publication Date：2026-03-30

Online Publishing Date：2026-03-18(First online date of this platform, not the publication date of the document)

Pages：11( 1211-1221 )

Neural Regeneration Research

ISTICSCICSCD

ISSN：1673-5374

Year, Vol.(Issue)：2026,21(3)