Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis
Laura Huggon
Emma L.Clayton
Abstract：Frontotemporal dementia and amyotrophic lateral sclerosis: Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases with significant overlapping attributes. While these neurodegenerative diseases affect different neuronal populations (with FTD affecting neurons of the frontal and temporal lobes, and ALS affecting upper and lower motor neurons), these two diseases are complexly intertwined.
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Publication Date：2025-11-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 3217-3218 )