Iron-handling solute carrier SLC22A17 as a blood-brain barrier target after stroke
Xueqi Ren
Wenlu Li
Abstract：The pathophysiology of ischemic stroke is complex and multifactorial, involving various forms of cell death such as apoptosis, autophagy, and necrosis. A recent study suggests that oxidative and inflammatory stress can induce ferroptosis, a specialized form of cell death characterized by the accumulation of lipid peroxides dependent on intracellular iron overload (Li and Jia, 2023).
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Publication Date：2025-11-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 3207-3208 )