Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration
Marianne Bardy-Lagarde
Narimène Asbelaoui
Abdel Mouman Ghoumari
Abstract：Multiple sclerosis (MS) is the most common chronic disease of the central nervous system (CNS) in young adults and represents the first cause of severe handicap, originally non-traumatic (Oh et al., 2018). MS is characterized by the infiltration of auto reactive lymphocytes specific to myelin through the blood-brain barrier, which results in the appearance of inflammatory demyelinating lesions caused by the death of the central nervous system myelinating cells, oligodendrocytes (Oh et al., 2018). There is a prevalence sexual with a ratio of three times more affected women than men.
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Publication Date：2025-09-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 2581-2582 )