Nucleoside modified mRNA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord
Krisztián Pajer
Tamás Bellák
Antal Nógrádi
Abstract:Spinal cord injury and treatment opportunities: The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular factors. Although the spinal cord neurons have the capacity to regenerate their axons, the expression of growth inhibitory factors, lack or suppression of proper guidance cues, and profound inflammatory responses do not permit successful regeneration (Khyeam et al., 2021).
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Publication Date:2025-08-27
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:2( 2311-2312 )
