Contribution of mechanical forces to structural synaptic plasticity:insights from 3D cellular motility mechanisms
Rita O.Teodoro
Mafalda Ribeiro Ramos
Lara Carvalho
Abstract：Cells, tissues, and organs are constantly subjected to the action of mechanical forces from the extracellular environment—and the nervous system is no exception. Cell-intrinsic properties such as membrane lipid composition, abundance of mechanosensors, and cytoskeletal dynamics make cells more or less likely to sense these forces. Intrinsic and extrinsic cues are integrated by cells and this combined information determines the rate and dynamics of membrane protrusion growth or retraction (Yamada and Sixt, 2019).
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Publication Date：2025-07-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 1995-1996 )