Sleep as a window to understand and regulate Alzheimer's disease:emerging roles of thalamic reticular nucleus
Haoqi Sun
Shiqian Shen
Robert J.Thomas
M.Brandon Westover
Can Zhang
Abstract：Introduction: Alzheimer's disease (AD) is a common neurodegenerative disorder and the primary cause of dementia. Considerable evidence supports the 'amyloid hypothesis,' stating that the pathogenesis of AD is primarily caused by the deposition of amyloid-β (Aβ), which drives tau phosphorylation, neuroinflammation, and neurodegeneration in the brain.
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Publication Date：2025-06-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 1711-1712 )