Research advances in mechanical thrombectomy for medium and distal cerebral vascular occlusions
Zhao Kaijie
Shao Shaoju
Zhang Guozhen
Sun Xiuting
Zhang Xiaoyan
Abstract：Mechanical thrombectomy has established efficacy in treating acute ischemic stroke caused by large vessel occlusion.However,for acute ischemic stroke associated with distal medium vessel occlusion(MeVO),endovascular recanalization remains challenging due to small vessel diameter,tortuous anatomy,and limited distal perfusion territory.As there is insufficient evidence to support application of mechanical thrombectomy for distal MeVO,it is not currently established as a standard indication for endovascular therapy.With advancements in the miniaturization and navigability of interventional devices,distal MeVO is gradually emerging as a potential target for mechanical thrombectomy.Nevertheless,occlusion of perforating arteries remains unsuitable for this technique due to their excessively small vessel caliber.This article reviewed the anatomical features and classification,imaging diagnosis,relevant clinical research,and novel materials and technologies pertaining to distal MeVO,aiming to provide reference for recanalization strategies in patients with this condition.
Keywords：Ischemic strokeMechanical thrombectomyMedium vessel occlusionReview
Publication Date：2025-06-18
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：9( 430-438 )