Bilateral medial medullary infarction:a report of two cases and literature review
Huang Sichun
Zhang Zhongsheng
Kong Xuejian
Cheng Jiaxin
Abstract：Bilateral medial medullary infarction(MMI)is a rare type of posterior circulation stroke,which is easily misdiagnosed as Guillain-Barré syndrome,myelitis,and other diseases in the early stages of onset,and has a poor overall prognosis.Early diagnosis and correct treatment are urgently needed.The authors reviewed two patients recently diagnosed with bilateral MMI.Both patients suffered from acute attacks,with one patient suffering from acute Guillain-Barré syndrome like symptoms(rapid progressive quadriplegia and difficulty in pronunciation),and the other patient presenting mainly with bilateral limb weakness and numbness.Experienced clinicians can quickly make accurate diagnoses by collecting information such as medical history,symptoms,signs,and patterns of onset(acute attacks,especially during sleep or rapid deterioration during sleep),combined with diffusion weighted imaging.With early intensified triple antiplatelet therapy,symptoms of both patients relieved rapidly.The aim of this study is to describe the mechanism,clinical manifestations,neuroradiological features and treatment of stroke,to provide reference for early diagnosis and effective treatment.
Keywords：Bilateral medial medullary infarctionQuadriplegiaEarly diagnosisPlatelet aggregation inhibitor
Publication Date：2024-01-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 55-58 )