Factors associated with postoperative enteral feeding intolerance in patients with hypertensive intracerebral hemorrhage
LIU Xin
XING Hong-wei
WANG Chuan-hua
ZHANG Gao-jian
WANG Ru-hai
WANG Shen
ZHANG Min
Abstract：Objective To investigate the risk factors for enteral feeding intolerance(EFI)after surgery for hypertensive intracerebral hemorrhage(HICH).Methods The clinical data of 205 HICH patients who underwent surgery between January 2021 and June 2023 were retrospectively analyzed.Multivariate logistic regression was used to identify independent risk factors for postoperative EFI,and receiver operating characteristic(ROC)curves were employed to assess their predictive power.Results Within 2 weeks postoperatively,EFI occurred in 113 patients(55.12%).Multivariate analysis identified the following independent risk factors for EFI:brain herniation(OR=6.657;95%CI:1.206～36.746;P=0.030),hemorrhage rupturing into the ventricles(OR=4.131;95%CI:1.999～8.536;P<0.001),prolonged mechanical ventilation duration(OR=1.268;95%CI:1.150～1.399;P<0.001),and elevated postoperative neutrophil-to-lymphocyte ratio(NLR)(OR=1.097;95%CI:1.047～1.149;P<0.001).ROC analysis showed AUC values for predicting EFI as follows:brain herniation was 0.564,hemorrhage rupturing into the ventricles was 0.658,mechanical ventilation duration was 0.775,and postoperative NLR was 0.665;the combined predictive AUC of all four indicators was 0.854(95%CI:0.798～0.899;P<0.001).Conclusion Brain herniation,hemorrhage rupturing into the ventricles,prolonged mechanical ventilation,and elevated postoperative NLR are independent risk factors for EFI after HICH surgery.Combined use of these indicators significantly enhances EFI prediction.
Keywords：Hypertensive intracerebral hemorrhageSurgeryEnteral feeding intoleranceRisk factors
Publication Date：2025-04-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 217-222 )