Cranial-nasal-orbital extranodal marginal zone B-cell lymphoma:a case report
BO Ming-tao
LIU Hai-tao
NIU Ji-jie
ZHUANG Xu-wei
LI Xiao-long
ZHANG Yu-hai
Abstract：Cranio-nasal-orbital non-Hodgkin's lymphoma,as a form of primary central nervous system lymphoma and a subtype of extranodal non-Hodgkin's lymphoma,is clinically rare,accounting for approximately 1.6%of all intracranial malignant tumors and 1%～2%of extranodal lymphomas.The malignancy of this disease is extremely high.The aim of surgery is to clarify the pathology and alleviate the space-occupying effect of the tumor.The main treatment modalities are radiotherapy and chemotherapy,yet the overall prognosis is unfavorable.This paper presents a case of cranio-nasal-orbital non-Hodgkin's B-cell lymphoma in a 66-year-old female.A surgical biopsy was performed,and the postoperative pathology confirmed non-Hodgkin's B-cell lymphoma.The patient died one month after the surgery.In conclusion,cranio-nasal-orbital non-Hodgkin's large B-cell lymphoma is relatively rare in clinical settings and is often misdiagnosed as nasopharyngeal carcinoma,orbital tumors,or retrobulbar optic neuritis,among others.A clear diagnosis can mostly be achieved through pathological examinations.The malignancy of this disease is extremely high.Relying solely on surgery does not significantly prolong the survival period.The main treatments are radiotherapy and chemotherapy,which are conducive to the control of local lesions,but the overall prognosis is poor.Hence,accurate and early diagnosis of this disease is of paramount importance.
Keywords：Cranio-nasal-orbital tumorsNon-Hodgkin's lymphomaTreatmentPrognosis
Publication Date：2024-12-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 767-768 )