New progress of immunogenic cell death inducers in the treatment of glioma
SUN Zhi-qiang
CHEN Qian-xue
Abstract：Glioma is the most common primary malignant tumor in the central nervous system.Even with comprehensive treatments such as surgery combined with postoperative concurrent chemoradiotherapy,the therapeutic efficacy is still poor.Immunogenic cell death(ICD),a newly discovered form of regulated cell death,can be induced by various chemotherapeutic drugs,physical stimuli,and biological agents,causing cells to release multiple types of damage-associated molecular patterns,thereby recruiting and activating various immune cells and generating adaptive immune responses against specific antigens.ICD has also been widely employed to induce anti-tumor immune therapy for glioma.This paper briefly summarizes the latest advancements in ICD and its related inducers.
Keywords：GliomaImmunogenic cell deathImmunogenic cell death inducersDamage-associated molecular patterns
Publication Date：2024-12-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 756-760 )