Solitary fibrous tumor within the brain parenchyma:a case report

XIONG Hai-bing; XIONG Hao-feng; HUO Jian-hong; ZENG Shi

doi:10.13798/j.issn.1009-153X.2024.11.016

Abstract：Solitary fibrous tumor(SFT)is a spindle cell tumor originated from CD34-positive dendritic mesenchymal cells,which can occur in multiple parts of the body,most commonly in the thorax and abdomen,and is relatively rare in the brain.Although SFT is pathologically defined as a mesenchymal non-meningeal tumor,intracranial SFT usually grows along the meninges and is often misdiagnosed as meningioma before surgery.SFT within the brain parenchyma is even rarer.This paper reports a case of a 56-year-old male with a solitary fibrous tumor in the left frontal lobe.He was admitted to the hospital due to dizziness for one month and a space-occupying lesion in the brain was found one week ago.There were no obvious positive neurological signs.Head CT and MRI showed a space-occupying lesion in the left frontal lobe.Under general anesthesia,a left frontal lobe lesion resection was performed.During the operation,the tumor was found to be located in the white matter of the left frontal lobe,with a tough texture and clear boundaries.Postoperative pathological examination confirmed SFT(WHO grade I).Three months after the operation,a head MRI review showed no tumor recurrence.In conclusion,SFT within the brain parenchyma is extremely rare,mostly benign,with a high rate of clinical misdiagnosis.Imaging examinations have certain specificity,and the diagnosis depends on pathological examination.Surgical total resection is the main treatment method,and the prognosis is generally good.