Two cases of meningeal metastasis from prostate cancer
JIA Wen-xue
WANG Ji
ZHU Yue-feng
LIU Yan-ting
AI Wen-bing
TIAN Chun-lei
Abstract：Prostate cancer ranks as the second most prevalent malignancy in men globally.The aging population in China has contributed to a notable increase in prostate cancer incidence.Notably,prostate cancer frequently metastasizes distantly,with bone metastasis being predominant and brain metastasis rare.Brain metastases from prostate cancer typically manifest in advanced stages of the disease and are associated with a poor prognosis due to limited early screening modalities and clinical interventions.This paper reports two cases of meningeal metastases originating from prostate cancer.One case involved a 64-year-old patient who underwent surgical resection followed by postoperative radiotherapy and endocrine therapy,achieving independent living at a 5-month follow-up.The other case featured a 70-year-old patient who underwent surgery without adjuvant radiotherapy or chemotherapy,also attaining independent living at a 6-month follow-up.Therefore,when differentiating meningeal space-occupying lesions in elderly men,consideration should be given to the potential of a prostate origin.For patients presenting with meningeal metastases stemming from prostate cancer,if the patient's general condition is good and the extracranial disease is well controlled,surgical resection combined with radiotherapy and chemotherapy can help prolong the patient's survival outcomes.
Keywords：Brain metastasisProstate cancerMicrosurgeryPrognosis
Publication Date：2024-04-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 248-250 )