A case of Guillain-Barré syndrome after embolization of ruptured intracranial aneurysm
HONG Xiao-kang
WU Chang-chen
HUANG Xin-yuan
GUAN Feng
WANG Fan
Abstract：Guillain-Barré syndrome(GBS)is an autoimmune neurological disorder characterized by weakness and decreased muscle tone in the limbs.The decrease in limb muscle strength that occurs after endovascular embolization for ruptured intracranial aneurysms is generally considered symptomatic vasospasm,usually occurring 4～10 days after surgery.This article reports a case of a 55-year-old male with a ruptured aneurysm at the C6 segment of the left internal carotid artery who suddenly developed progressive limb weakness,decreased muscle tone in all limbs,and absent tendon reflexes 12 days after endovascular embolization.The diagnosis of GBS was confirmed by comprehensive neurological examinations,cerebrospinal fluid viral antibody testing,and serum peripheral nerve antibody testing.The patient recovered and was discharged after receiving immunoglobulin therapy,and normal recovery was observed during a 7-month follow-up.This suggests that when limb muscle weakness without a clear cause occurs during the cerebral vasospasm period after endovascular embolization of ruptured intracranial aneurysms,GBS should be considered,and early diagnosis is crucial for preventing the delay of the disease's diagnosis and enabling timely treatment.
Keywords：Ruptured intracranial aneurysmsEndovascular embolizationGuillain-Barré syndrome
Publication Date：2024-03-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 187-189 )