Research progress on the mechanism of cell death in cognitive impairment after traumatic brain injury
CHEN Zhen-huan
LI Meng-zhu
PAN Qi-hang
CHEN Zhuo-ying
TIAN Ya-hui
XIA Yu
LI Jun
Abstract：Traumatic brain injury(TBI)refers to functional or pathological changes in brain tissues caused by external forces on the head.Traumatic brain injury-related cognitive impairment(TBI-CI)is a characteristic manifestation of post-traumatic brain injury sequelae,and programmed cell death(PCD)processes such as apoptosis,necroptosis,pyroptosis,ferroptosis,and cuproptosis play a role in the pathological processes of TBI-CI.This review provides an overview of the research progress on the mechanisms of PCD in TBI-CI,aiming to offer insights for the prevention and treatment of clinical TBI-CI.
Keywords：Traumatic brain injuryCognitive impairmentProgrammed cell death
Publication Date：2024-02-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 111-114 )