Efficacy of endoscopic endonasal transsphenoidal surgery for patients with symptomatic Rathke's cleft cysts
PU Tian-you
HAN Guo-qiang
LIU Chuang-xi
WU Min
ZHANG Hai-wang
LUO Tao
Abstract：Objective To investigate the clinical characteristics of symptomatic Rathke's cleft cysts(RCCs)and the outcomes of endoscopic endonasal transsphenoidal surgery(EETS)for RCCs.Methods The clinical data of 53 patients with symptomatic RCCs who underwent EETS form August 216 to August 2021 were analyzed retrospectively.Results Forty-four patients presented with headache and dizziness,43 with abnormal visual evoked potentials,27 with visual impairment,23 with visual field defect,and 29 with pituitary hormone dysfunction.MRI showed that the maximum diameter of cysts ranged from 10 to 38 mm,with an average of(15.2±0.8)mm.The cysts'diameter≤15 mm were found in 36 patients and>15 mm in 17 patients.The main bodies of cysts were located intrasellarly in 25 patients and intrasellar-suprasellarly in 28.The cysts were totally resected in 30 patients,and great partially or drainage in 23.Electrolyte disturbance occurred in 25 patients,hypopituitarism in 14,cranial nerve injury in 7 and cerebrospinal fluid rhinorrhea in 4 after operation.The patients were followed up for 3～60 months after discharge,with an average of(13.5±5.6)months.Six patients(11.3%)recurred,and the recurrence time was 13～52 months,with an average of(21.5±4.9)months.Two patients were re-operated and four were followed up.Conclusions The clinical manifestations of symptomatic RCCs are varied and lack of specificity.MRI is the main method of preoperative evaluation.The efficacy of EETS is good for patients with symptomatic RCCs.
Keywords：Rathke's cleft cystRadiological featuresClinical featuresEndoscopic endonasal transsphenoidal surgeryEfficacy
Publication Date：2024-01-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1-3 )