Risk factors for multiple organ dysfunction in elderly patients with severe traumatic brain injury
XU Yang
CUI Hui-qin
XU Ting
GU Ren-li
Abstract：Objective To investigate the risk factors for multiple organ dysfunction(MODS)in elderly patients(≥60 years)with severe traumatic brain injury(sTBI).Methods The clinical data of 156 elderly patients with sTBI treated from March 2018 to February 2023 were retrospectively analyzed.During hospitalization,MODS were diagnosed according to the criteria of the 1995 National Conference on Critical Care and Emergency Medicine.Results Of these 156 patients,52 patients(33.33％)suffered from MODS.Multivariate logistic regression analysis showed that low admission GCS score,intracranial infection,high APACHE-Ⅱ score,decreased arterial blood PH and prolonged APTT were independent risk factors for MODS in the elderly patients with sTBI.ROC curve analysis showed that the area under the curve of the regression model constructed based on the above risk factors predicting MODS in the elderly patients with sTBI was 0.93(95％ CI:0.87～0.96),the sensitivity was 84.62％(95％CI:71.9％～93.1％),and the specificity was 95.19％(95％ CI:89.1％～98.4％).Conclusions MODS is a common complication of elderly patients with sTBI.The regression model constructed in this paper can predict MODS to some extent.
Keywords：Severe traumatic brain injuryElderly patientsMultiple organ dysfunctionRisk factors
Publication Date：2023-12-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 705-707,711 )