Electromyographic characteristics of peripheral neuropathy caused by laughing gas abuse
SHEN Dan-dan
JIANG Hong
Abstract：Objective To explore the electromyographic characteristics of peripheral neuropathy(PN)caused by nitrous oxide abuse.Methods A total of 124 patients with nitrous oxide abuse treated in our hospital from May 2019 to May 2023 were selected as subjects.PN was diagnosed using the Toronto Clinical Scoring system(TCSS),and PN was defined as TCSS score≥6 points.Results PN occurred in 78 of the 124 patients(62.90%,78/124).Compared with patients without PN,MCV and CMAP amplitude of common peroneal nerve,median nerve and ulnar nerve were significantly decreased in PN patients(P<0.05),SCV and SNAP amplitude of superficial peroneal nerve,median nerve and ulnar nerve were significantly decreased(P<0.05).Multivariate logistic regression analysis showed that decreased MCV and CMAP amplitude of common peroneal nerve,median nerve and ulnar nerve,and decreased SCV and SNAP amplitude of superficial peroneal nerve,median nerve and ulnar nerve were risk factors for PN in nitrous gas abuse patients(P<0.05).The predictive model constructed according to these risk factors had good predictive value,and the area under ROC curve was 0.845(95%CI 0.790～0.900;P<0.001).Conclusions There are abnormal changes in electromyogram of PN caused by nitrous oxide abuse.Electromyogram detecting is helpful for early identification of PN in patients with nitrous oxide abuse.
Keywords：Nitrous oxide abusePeripheral neuropathyElectromyographic characteristics
Publication Date：2023-10-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 625-627,631 )