Factors related to blood stream infection in neurosurgical patients with ventilator-associated pneumonia
XIE Zhao-yun
XIONG Yun
MENG Gui-luan
LI Yao-fu
YANG Zhong-ling
Abstract：Objective To analyze the factors related to blood stream infection (BSI) in the neurosurgical patients with ventilator-associated pneumonia (VAP) in order to put forward its intervenient measures. Methods The clinical data of 387 neurosurgical patients with VAP from April, 2013 to March, 2019 were analyzed retrospectively. Of these 387 patients, 112 suffered from BSI and 275 did not. The factors related to BSI were statistically analyzed. Results The rate of occurrence of BSI was 28.94% in these 387 patients. The multivariate logistic regression analysis showed that the independent risk factors related to BSI in the neurosurgical patients with VAP included the delayed VAP, acute physiology and chronic health evaluationⅡscores≥15 points, serum level of procalcitonin≥2 ng/ml, mechanical ventilation time≥7 d, use of glucocorticoid, blood sugar≥11.1mmol/L and tracheotomy. Conclusion In order to reduce BSI in the neurosurgical patients with VAP, we should timely evaluate the main measures to prevent BSI such as early catheterization, focusing on patients with severe illness, controlling blood glucose, reasonable use of glucocorticoid, reducing tracheotomy and reducing the occurrence of delayed VAP. The serum level of procalcitonin may be helpful to early prediction of BSI in the neurosurgical patients with VAP.
Keywords：NeurosurgeryVentilator-associated pneumoniaBlood flow infectionRelated factorsLogistic regression analysis
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 473-475,479 )