Analysis of risk factors related central nervous system infection in patients in neurosurgical intensive care unit
YU Jie
JI Yuan-yuan
WANG Jun
Abstract：Objective To analyze the risk factors of nosocomial acquired central nervous system (CNS) infection in the patients in neurosurgical intensive care unit (NICU).Methods The clinical data of 853 patients who were treated in the NICU from January to December,2016 were analyzed retrospectively.The risk factors related to CNS infection were statistically analyzed.Results CNS infection occurred in 31 (3.63%) of 853 patients.Univariate analysis showed that the factors related to CNS infection in those patients included the patients' age,activities of daily living (ADL) score on admission,emergency admission,leukopenia,hyperglycemia,surgery,subtentorial craniotomy,operation duration＞4 hours,non type I incision,intraoperative blood loss≥1000 ml,drainage tube placement,lumbar cistern drainage and drainage tube placement≥3 days.Multivariate analysis showed that the independent risk factors of CNS infection in neurological ICU patients included the patients' age＜60 years old (P＜0.01),leukopenia (P＜0.01),subtentorial craniotomy (P＜0.01) and drainage tube placement (P＜0.01).Conclusion The patients with the above risk factors should be paid close attention to and take precautions of CNS infection as early as possible.
Keywords：Neurosurgical intensive care unitCNS infectionRisk factors
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 204-206 )