Analysis of risk factors of blood stream infection in Department of Neurosurgery
XIE Zhao-yun
XIONG Yun
LI Zhong-hua
MENG Gui-luan
LI Yao-fu
YANG Zhong-ling
Abstract：Objective To investigate the characteristics and risk factors of blood stream infection in Department of neurosurgery. Methods The clinical data of 1 573 neurosurgical patients treated from June, 2014 to January, 2018 were analyzed retrospectively. Results The blood stream infection rate was 8.01% in 1 573 neurosurgical patients. The univariate analysis showed that the factors related to the neurosurgical patients'bloodstream infection included the patients'age, history of diabetes, admission to ICU, APACHEⅡ score, deep vein catheterization, coma, tracheotomy, indwelling bladder catheter, administration of glucocorticoid, blood glucose, peripheral blood leukocytes, percentage of peripheral blood neutrophils, and serum levels of C-reactive protein and procalcitonin (P<0.05). The multivariate logistic analysis showed that the independent risk factors of the neurosurgical patients' bloodstreams infection included the deep venous catheterization, mechanical ventilation, indwelling bladder catheter, administration of glucocorticoid, serum procalcitonin>0.5 ng/ml, and blood glucose>11.1 mmol/L (P<0.05). Conclusion The main measures to reduce neurosurgical patients' bloodstream infection should include the correct assessment of disease condition, reduction of unnecessary invasive methods of the diagnosis and treatment, rational administrastion of glucocorticoid, control of the blood sugar, monitoring of the serum procalcitonin, and early prevention and treatment of the bloodstreams infection.
Keywords：Neurosurical patientsBloodstream InfectionRisk factorsStatistical analysis
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 31-34 )