Contact aspiration versus stent thrombectomy for large vessel ischemic strokes: a meta-analysis of randomized controlled trials
ZHAO Wen-ke
ZHANG Peng-fei
HUANG Chang-heng
YAO Zi-tong
WEI Meng-guang
YU Yao-yu
Abstract：Objective To compare the effectiveness and safety of contact aspiration with those of stent thrombolysis within 6 hours after onset of stroke in patients with large vessel ischemic stroke. Methods The Pubmed, Embase, ClinicalTrials.gov and Cochrane databases were searched by computer for randomized controlled trials of stent thrombectomy and contact aspiration for the large vessel ischemic stroke. Meta analysis was performed with review manager 5.3 software. Results A total of 9 articles which were enrolled in this study included 2 851 patients. The results of Meta-analysis showed that there were no significant differences in the postoperative vascular reperfusion and the rate of adverse events between contact aspiration group and stent thrombectomy group. The rale of death was significantly higher in the stent thrombectomy group than that in the contact aspiration group (OR=7.59, 95％ CI: 1.94～29.72, P=0.004). There was no significant difference in the rate of good prognosis between both the groups. Conclusion The contact aspiration technique is similar to the stent thrombectomy in the postoperative vascular reperfusion and adverse events, but the rate of death is significantly lower in the patients with large vessel ischemic stroke receiving contact aspiration than that in the patients with large vessel ischemic stroke receiving stent thrombectomy.
Keywords：Ischemic strokeContact aspirationStent thrombectomyLarge vesselsMeta-analysis
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 388-391 )