Relationship between serum hormone level and tumorous volume in patients with functional pituitary adenomas after Gamma Knife treatment
LI Lei
WU Ting-ting
XIE Wen-tao
LI Xue-tao
CAO Hong-ming
ZHAO Ning-hui
SHI Guo-lin
Abstract：Objective To explore the relationship of serum hormone level with tumorous volume in the patients with functional pituitary adenomas. Methods Of 72 patients with functional pituitary adenomas, 32 had growth hormone adenomas and 40 prolactin adenomas. The serum hormones levels and tumorous volumes were measured before the Gamma Knife treatments and 1.5 years after Gamma knife treatment in all the patients. The tumorous volumes and serum hormone levels were compared before and after Gamma Knife treatments by paired T-test.Results The tumorous volume was significantly smaller 1.5 years after Gamma knife treatment than that before the treatment(P<0.05).The serum hormone level were significantly lower 1.5 years after Gamma knife treatment than that before the treatment(P<0.05).Conclusion The results suggest that the change in the serum hormone level can reflect the change in the size of the tumor volume.The postoperative change in the serum hormone level is helpful to understanding the change in the tumorous volumes in the patients with functional pituitary adenomas receiving Gamma knife treatment.
Keywords：Functional pituitary adenomasProlactinGrowth hormoneGamma KnifeTumorous volumeHormone levelRelationship
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 155-157 )