Evaluation of executive function of frontal lobes in patients with blast craniocerebral injury by resting fMRI combined with WCST
GAO Yu-song
Lü Hong-di
HU Jun-hua
LUO Xin-min
HU Cheng-xiao
HU Song-po
CHAI Chao
LEI Ya-ping
Abstract：Objective To evaluate the executive function of frontal lobes in the patients with blast craniocerebral injury by brain function network constructed with resting functional magnetic resonance imaging (fMRI) and Wisconsin Card Sorting Test (WCST). Methods The resting fMRI was performed 3 months after the injury in 4 patients with blast craniocerebral injury and 6 healthy subjects serving as control in order to construct the brain nets and then the average frontal lobes degrees were calculated.WCST was performed at the same time in all the patients and the subjects.The differences in frontal lobe degree and WCST scores were compared between both the groups.The correlativity of the frontal lobes degree with WCST scores were analyzed by pearson correlation.Result The frontal lobes degree and WCST scores were significantly lower in patients with blast craniocerebral injury than those in the healthy subjects(P<0.05), although the WCST scores were in the normal range.Frontal lobes degree was significantly positively associated with the WCST scores in both the groups(P<0.05).Conclusion It is suggested that the frontal lobe networks 3 months after the injury in the patients with blast craniocerebral injury may have potential disturbance,which may lead to a decrease in executive ability shown by WCST in the normal range.
Keywords：Blast craniocerebral injuryWisconsin card sorting testFrontal lobe networkExecutive function
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 821-823 )