Meta-analysis of curative effects of lumboperitoneal shunts and ventriculoperitoneal shunts on communicating hydrocephalus
CAI Qing
HUAN Xiao-li
FENG Da-Yun
QIN Huai-zhou
Abstract：Objective To analyze the clinical effects of lumboperitoneal shunt (LPS) and ventriculoperitoneal shunt (VPS) on communicating hydrocephalus and their safety. Methods The articles of randomized controlled trials and non-randomized concurrent controlled trials of communicating hydrocephalus treated by LPS and VPS published from January, 2010 to October, 2015 were searched from the data bases including PubMed, The Cochrane Library, EMbase, CNKI, CBM, VIP and WanFang Data base. According to the inclusion criteria, two reviewers independently screened articles, extracted data, and evaluated and cross-checked the quality of the included studies. Then meta-analysis was performed by RevMan 5.3 software. Results A total of 11 randomized controlled trials or non-randomized concurrent controlled trials including 891 participants were derived from the above-mentioned data bases. The results of meta analysis showed that the occurrence rates of the postoperative overall complications, infection, valve related complication and over-drainage/ under-drainage were significantly lower in LPS group than those in VPS group (P<0.05), the effctive rate was significantly lower in LPS group than that in VPS group (P<0.05). Conclusions Current evidence suggests that LPS is superior to VPS in decreasing the occurrence rates of overall complications, infection, valve related complication and over-drainage/under-drainage rates, but LPS is inferior to VPS in overall effective rate in the patients with communicating hydrocephalus.
Keywords：Communicating hydrocephalusVentriculoperitoneal shuntLumboperitoneal shuntsCurative effectsMeta-analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 764-766,770 )