Meta-analysis of opportunity of endoscopic endonasal optic canal decompression in patients with traumatic optic neuropathy
XIE Li-ping
LIN Tao
SHU Kun
FENG Lei
SU Long
CHE Hai-jiang
WANG Peng
Abstract：Objective To evaluate the opportunity of neuroendoscopic endonasal optic canal decompression (NEEOCD) for the traumatic optic neuropathy (TON). Methods According to the principle of evidence-based medicine, the data bases such as Medline, EMBase, Cochran library, CNKI,WANFANG and VIP were searched in order to retrieve the original articles of NEEOCD for TON from January, 1991 to January, 2017. Meta-analysis and data processing were done by the Rev. Man5.3 software. Results A total of 11 original articles including 879 patients with TON undergoing NEEOCD were involved in the meta-analysis. Meta-analysis showed that the total effective rate was significantly higher in the patients with TON who underwent NEEOCD within 3 days after the injury than that in the patients with TON undergoing NEEOCD more than 3 days after the injury [OR (95%CI) 2.53 (1.34,4.76);P<0.01]. The effective rate was significantly higher in the TON patients without preoperative blinding who underwent NEEOCD within 3 days after the injury than that in the TON patients without preoperative blinding who underwent NEEOCD more than 3 days after the injury [OR (95%CI) 2.31 (1.12, 4.79);P=0.02]. Conclusion It is suggested that NEEOCD should be performed as early as possible in order to improve the prognoses in the patients with TON.
Keywords：Traumatic optic neuropathyNeuroendoscopeEndonasal optic canal decompressionSurgical opportunityMeta-analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 761-763,794 )