Analysis of factors related to postoperative prognoses in focal cortical dysplasia patients with refractory epilepsy
WANG Yi-he
ZHAO Guo-guang
SHAN Yong-zhi
FAN Xiao-tong
AN Yang
LU Chao
Abstract:Objective To analyze the surgical outcomes and factors related to postoperative prognoses in focal cortical dysplasia (FCD) patients with refractory epilepsy. Methods The clinical data the 97 FCD patients with refractory epilepsy treated in Department of Neurosurgery, Xuanwu Hospital, Capital Medical University from May, 2007 to November, 2015 were analyzed retrospectively. Results The mean follow-up time in these 97 patients was (59.18 ± 28.62) months. The epilepsy control reached Engel grade I in 60 patients, gradeⅡin 11, gradeⅢin 16 and gradeⅣin 10. The prognoses of postoperative FCD patients with refractory epilepsy were related to MRI results (positive or negative) and the resection extent of epileptogenic zone. Conclusion The present results show that the effects of surgery on the refractory epilepsy in the patients with FCD are good. MRI positive results and total resection of epileptogenic zone are the favorable prognosis factors in FCD patients with refractory epilepsy.
Keywords:Focal Cortical DysplasiaRefractory epilepsyPrognostic factorsLong-term outcome
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 737-740 )
