Application of ROSA-guided stereoelectroencephalography surgery for intractable epilepsy in children

CHEN Jun-xi; GUO Qiang; TAN Hong-ping; WANG Geng-bo; HUA Gang

doi:10.13798/j.issn.1009-153X.2017.09.005

Abstract：Objective To explore the safety of intracranial electrode implantation under help of Robotized stereotactic assistant (ROSA)-guided stereoelectroencephalography (SEEG) and its value to surgery for intractable epilepsy in children. Methods Nineteen children under 14 years of age with intractable epilepsy were preoperatively assessed by MRI, video-EEG, PET-CT and so on and then the implantation of intracranial electrode, by which the long-term intracranial EEG was recorded, was performed under the help of ROSA-guided SEEG in order to locate the epileptogenic zone. The surgery was performed after the location of the epileptogenic zone in all the patients. Results A total of 222 intracranial electrodes were successfully implanted in all the children. The electrodes were implanted in the left cerebral hemisphere in 11 children, in the right ones in 7 and in bilateral ones in 1. There were no complications such as bleeding, cerebrospinal fluid leakage, electrode fracture and infection in all the children after the implantation. The epileptogenic zones were exactly located and successfully resected by surgery in all the children. Two patients had transient hemiparesis after the surgery. The following up from 12 to 24 months showed that the epileptic control effect was Engel gradeⅠin 15 children, gradeⅡin 1, gradeⅢin 1 and gradeⅣin 2. Conclusions The intracranial electrode implantation under the help of ROSA-guided SEEG is safe and may decrease in the postoperative complications and improvement of prognosis in the children with intractable epilepsy.