Application of lipid scalp markers to the design of electrode track for deep brain stimulation in patients with movement disorders
CHEN Li-dao
LIU Wen
ZHANG Jie
FU Kai
ZHANG Ji-bo
LIU Xue-meng
PENG Qi-zhen
DING Wei
Abstract：Objective To explore the value of lipid pellet serving as scalp marker to the design of electrode track for deep brain stimulation (DBS) during MRI locating scan in the patients with movement disorders. Methods Of 104 patients (187 sides) with movement disorders treated with DBS from November, 2011 to April, 2017, 45 (84 sides, observed group) received the lipid pellets (serving as markers)-assisted design of electrode tracks and 59 (103 sides, control group) not. Of 104 patients with movement disorders, 96 suffered from Parkinson's disease, 3 essential tremor and 5 dystonia. The adjusted distance of the electrode entry point was measured. The hemorrhage in the electrode tracks and the electrode track passed the lateral ventricle were observed and recorded. Unified Parkinson Disease Rating scale scores (UPDRS III) under the stimulation conditions were determined in all the patients before the surgery and after the surgery. Results In the observed group, the electrode entry points of 48 sides (57.1%) were adjusted under the guidance of lipid pellets and the adjusted distances ranged from 3 to 10 mm. The CT scan showed that the asymptomatic subcortical hemorrhage around the track in 1 side in the observed group. In the control group, MRI showed that the tracks passed the lateral ventricles in 5 sides and asymptomatic subcortical hemorrhage in 3 sides was found. The rate of postoperative complication was significantly lower in obseraved group (1.2%, 1/84) than taht (7.8%, 8/103) in control group (P<0.05). UPDRS scores 1 month after the surgery were (16.0±9.5) points and (14.7±7.5) points respectively in the observed and control groups. There was no significant difference in UPDRS scores 1 month after the surgery between both the groups (P>0.05). Conclusion The lipid pellet (severing as scalp marker)-assisted design of the electrode track for DBS is simple and feasible in the patients with PD and can reduce bleeding in the electrode track and avoid passing the lateral ventricle.
Keywords：Movement disordersDeep brain stimulationDesignElectrode trackLipid pellet
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 619-622 )