Curative effect of aspirin combined with plavix on ischemic stroke and its impact on platelet aggregation rate
DUAN Fa-liang
HUANG Cong-gang
NI Hou-jie
MIN Qiang
HUANG Qiao-chun
WU Jing-lei
WANG Yuan
SONG Ping
Abstract：Objective To investigate the curative effect of aspirin combined with plavix on ischemic stroke and its impact on platelet aggregation rate.Methods The clinical data of 292 patients with ischemic stroke,of whom,146 patients were treated by routine treatment and aspirin (100 mg,qd;routine group) and 146 patients were treated by plavix (75mg,qd) on the basis of routine and aspirin treatments (combined group) from June,2014 to June,2015,were analyzed retrospectively.The platelet aggregation rate was determined and the neurological defect was determined in all the patients by National Institute of Health stroke scale (NIHSS) score before and 2 weeks after the treatment.Results The platelet aggregation rates and NIHSS scores in both the combined and routine groups were significantly lower after the treatment than those before the treatment (P＜0.05).The platelet aggregation rates and NIHSS scores were significantly lower in the combined group than those in the routine group 2 weeks after the treatment (P＜0.05).Conclusion Aspirin and plavix can play a synergistic role in decrease of the platelet aggregation rate in the patients with ischemic stroke.The curative effect on the patients with ischemic stroke can be enhanced by aspirin combined with plavix.
Keywords：Ischemic strokeAspirinPlavixPlatelet aggregationCurative effect
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 470-472 )