Risk factors relate to intracranial infection after endoscope-assisted surgery through endonasal transsphenoidal approach for pituitary adenomas
QIAO Jian-hua
HAI Yan
Abstract：Objective To investigate the risk factors related to the intracranial infection after endoscope-assisted surgery through endonasal transsphenoidal approach for pituitary adenomas.Methods The clinical data of 123 patients with pituitary adenomas,who were treated by endoscope-assisted surgery through endonasal transsphenoidal approach from January,2012 to January,2016 were analyzed retrospectively.The risk factors related to the postoperative intracranial infection were analyzed by multivariate Logistic regression analysis.Results The rate of intracranial infection occurrence was 8.94％ (11/123).The multivariate Logistic regression analysis showed that the risk factors related to the intracranial infection after endonasal transspheaoidal surgery included diabetes,surgery time ≥4 h,cerebrospinal fluid leakage and preoperative use of hormone (P＜0.05).Conclusion The intracranial infection after the endoscopic endonasal transsphenoidal surgery is related to many factors including diabetes,surgery time ≥4 h,cerebrospinal fluid leakage,preoperative use of hormone.The susceptible patients with above-mentioned risk factors should be given more attention and preventive treatment in order to reduce the incidence of intracranial infection.
Keywords：Pituitary adenomasEndoscope-assisted surgeryEndonasal transsphenoidal approachIntracranial infectionRisk factors
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 413-415 )