Risk factors related to intracranial infection after craniotomy
LIU Rong-hua
DUAN Kui-jia
Abstract：Objective To explore the risk factors related to intracranial infection after craniotomy.Methods The clinical data of 1 049 patients undergoing craniotomy from October,2011 to October,2015,of whom,981 were included in this study and 68 were excluded from this study according to the inclusion criteria and exclusion criteria,were analyzed retrospectively.Of those 981 patients,41 (4.2％) had intracranial infection and 940 not according to the diagnostic criteria of the US Centers for Disease Control and Prevention.The risk factors related to intracranial infection were analyzed by statistics.Results The monofactorial analysis and multivariate logistic regression analysis showed that the risk factors related the intracranial infection after the craniotomy included the operative duration ＞4 hours,posterior cranial fossa surgery,external ventricular drainage (EVD),implanted material,cerebrospinal fluid leakage and diabetes mellitus.Conclusion Strict aseptic technique,use of effective antibiotics during perioperative period,strict suturing of dura mater,shortening operative and EVD time,avoiding unnecessary implantation of materials,and effectively control of blood glucose in the diabetic patients can effectively reduce intracranial infection after the craniotomy.
Keywords：CraniotomyIntracranial infectionRisk factorsStatistic analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 407-409 )