Application of PET-MR image fusion to temporal lobectomy in patients with temporal lobe epilepsy
WANG Guo-fu
YANG Ming
LUAN Guo-ming
ZHONG Xu-guang
LIN Yao-xin
Abstract：Objective To evaluate the value of PET-MR image fusion to anterior temporal lobectomy in the patients with temporal lobe epilepsy caused by hippocampal sclerosis.Methods From January,2013 to January,2015,10 patients with unilateral temporal lobe epilepsy caused by hippocampal sclerosis underwent surgical resection of the anterior temporal lobe according to low metabolism area showed by PET-MR image fusion.PET-CT and MRI were performed again 3 months after the operation,and the short-term complications and epilepsy control were assessed in all the patients1.9 year after the operation.Results The preoperative PET showed that there was low metabolism in the anterior temporal lobes of the affected sides in 10 patients,and the metabolism decreased in the bilateral temporal lobes in 2 patients.The postoperative pathological examination showed that there was anterior temporal lobe focal cortical dysplasia type Ⅰ in 8 patients and focal cortical dysplasia type [[in 2 patients.There were no short-term postoperative hemiplegia,aphasia and severe memory disturbance in all the patients.The epilepsy control belonged in Engel grade Ia in 8 cases,grade Ib in 1 case and grade Ic in 1 case.Conclusion The preoperative PET-MR imaging fusion is very helpful to accurate location of the extent of the anterior temporal lobectomy and can improve the control effect of the surgery on the epilepsy in the patients with temporal lobe epilepsy induced by hippocampal sclerosis.
Keywords：Temporal lobe epilepsyTemporal lobectomyPositron emission computed tomographyMRIImage fusion
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 372-375 )