Changes of plasma anterior pituitary hormone and CSF H2S in patients with acute craniocerebral trauma
XIAO Gao-hua
CHEN Gang
CHEN Zheng
LIU Ke
LIU Xiao
XIONG Shao-tang
Abstract：Objectve To investigate the relationship of the severity with levels of anterior pituitary hormones (APHs) and cerebrospinal fluid (CSF) hydrogen sulfide (H2S) in patients with acute crauiocerebral trauma (ACT).Methods Of 90 patients with ACT treated in the hospital from March,2014,to November,2015,30 suffered from mild ACT,30 from moderate ACT and 30 from severe ACT according to GCS.The levels of plasma APHs including thyroid-stimulating hormone (TSH),prolactin (PRL),luteotrophic hormone (LH),follicle-stimulating hormone (FSH) and growth hormone (GH) and CFS H2S were determined in all the patients 1 day after ACT.The relationship of severity with the levels of plasma APH and CSF H2S was analyzed.Results The levels of plasma GH and PRL and CFS H2S were significantly higher in the patients with severe ACT than those in the patients with moderate ACT (P＜0.05),which were significantly higher than those in the patients with mild ACT (P＜0.05).Conclusion It is suggested that the levels of plasma GH and PRL and CSF H2S which are positively related to the severity can be used as indicators of injury severity in the patients with ACT.
Keywords：Acute craniocerebral traumaAnterior pituitary hormoneH2SPlasmaCerebrospinal fluidLevel
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 310-312 )