Initial experience in embolizing intracranial aneurysms with new mechanical detachable coils (Presgo(R))

ZUO Qiao; XU Yi; HONG Bo; LIU Jian-min; HUANG Qing-hai

doi:10.13798/j.issn.1009-153X.2017.03.013

Abstract：Objective To analyze the safety of domestic-made Presgo(R) mechanical detachable coil and its curative effect on intracranial aneurysms.Methods Of 16 patients with intracranial aneurysms,7 received endovascular embolization of the aneurysms with Presgo(R) coils and 9 with domestic-made Jasper electronic detachable coils from August,2011 to September,2012 in the single center.The detachment function,embolization result,the rate of procedure-related adverse event occurrence rate and modified Rankin Scale (mRS) scores were compared between the two groups.Results The success rates of embolization with two types of coils were both 100％;The median detachment time of Presgo(R)coil was 5.0 s,which was significantly shorter than that of Jasper coil (45.0 s,P＜0.001).There was insignificant difference in the curative effects on the aneurysms between the two groups 6 months after the embolization (P=0.649).No aneurysms recurred in both the groups.There were insignificant differences in the occurrence rates of the procedure-related adverse events and the prognoses between both the groups (P＞0.05).Conclusions Presgo(R) mechanical detachable coil can be detached more quickly compared to Jasper electronic detachable coil.Presgo(R) mechanical detachable coil is similar to Jasper electronic detachable coil in the safety and occluding effect on the aneurysms.But the sample size in this study is very small,and it is necessary to for the clinical safety and efficacy of Presgo(R) coils be studied further with larger samples and long-term follow-up.