Clinical features and surgical treatment of patients with focal epileptogenic lesions and general interictal epileptiform discharges
MA Wei
WANG Chao
LI Huan-fa
WANG Wei-wen
JING Xiao-rong
DONG Shan
ZHANG Hua
Abstract：Objective To explore the clinical features and surgical outcomes of patients with focal epileptogenic lesions and general interictal epileptiform discharges (GIEDs). Method The electrophysiological and clinical data of 733 patients with focal epileptogenic lesions proved by MRI and GIEDs were analyzed retrospectively. Results The patients with GIEDs accounted for 8.2%(60/733) of the patients with focal epileptogenic lesions. There were features including younger age on seizure onset [patients with age≤12 years accounted for 80.0%(48/60) of all the patients with GIEDs], more lesions (14.9%, 26/175) located in the frontal lobe and a higher ratio of male to female (42:18) in 60 patients with IEDs. Of the 19 patients who underwent surgery and were followed up over 1 year, 13 belonged in Engel's classⅠ, 2 in classⅡ, 4 in classⅢ~Ⅳ. Conclusions GIEDs may appear in epilepsy patients with focal lesion, and surgical treatment is helpful to improving the prognosis in these patients.
Keywords：Focal epilepsyGeneral iterictal epileptiform dischargesElectrophysiologySurgery
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 521-522,575 )