Drug resistance of Gram-negative Bacilli in patients in NICU from 2011 to 2013
TIAN Jun
ZHU Xiu-mei
LI Qi
CHI Li-yan
WEI Liang-feng
ZHENG Zhao-cong
WANG Shou-sen
Abstract：Objective To study the drug resistance of Gram-negative bacilli in the patients in neurosurgery intensive care unit (NICU) in order to provide guidance for the rational use of antibiotics. Method From January, 2011 to December, 2013, the antimicrobial susceptibility test was performed in the Gram-negative bacilli isolated from the patients in NICU by minimum inhibitory concentration method. The results were analyzed by WHONET 5.3 Software. Results The first three pathogens of 363 strains were Acinetobacter spp (34.7%), Pseudomonas aeruginosa (24.5%) and Klebsiella pneumonia (20.4%) respectively. The resistance rate of Acinetobacter spp to amikacin and cefoperazone-sulbactam were 4.0% and 15.9% respectively. The resistance rate of pseudomonas aeruginosa to piperacillin-tazobactam was about 33.3%. Conclusions In NICU, imipenem cefoperazone-sulbactam and piperacillin-tazobactam remain high activity against Gram-negative bacilli in NICU.
Keywords：NeurosurgeryIntensive care unitGram-negative bacilliDrug resistance
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 422-424 )