Resection of pituitary adenomas by endoscopic and microscopic surgery via transnasal transsphenoidal approach：a comparative analysis
WANG Ya-ping
JIA Xiao-xiong
WANG-Jun
WANG Lin-lin
TAN Yi-tao
MA De-de
XIA He-chun
Abstract：Objective To compare the curative effect of endoscopic surgery via transnasal transsphenoidal approach on pituitary adenomas with that of transnasal transsphenoidal microsurgery on them. Methods The clinical data of 319 patients with pituitary adenomas, of whom, 127 underwent endoscopic surgery via transnasal transsphenoidal approach and 192 underwent microsurgery via transnasal transsphenoidal approach from January, 2010 to October, 2015 were analyzed retrospectively. Results The pituitary adenomas were definitely diagnosed by pathological examination. The rates of nasal septum defect, diabetes insipidus occurrence and tumors recurrence were 20.47%, 8.66%and 4.72%respectively in the endoscopic group, and they were 36.98%, 27.60%and 13.02%respec-tively in the microscopic group. There were significant differences in all the above-mentioned rates between both the groups (P<0.05). There were insignificant differences in the rates of the other complications occurrence and curative effect between the two groups (P>0.05). Conclusions The endoscopic surgery via transnasal transsphenoidal approach is similar to the microscopic surgery via transnasal transsphenoidal in the curative effects on the pituitary adenomas. But the endoscopic surgery via transnasal transsphenoidal approach has advantages including the lower rates of nasal septum defect and diabetes insipidus occurrence and tumorous recurrence compared to the microsurgery via the same approach in the patients with pituitary adenomas.
Keywords：Pituitay adenomasEndoscopic surgeryMicroscopic surgeryTransnasal transsphenoidal approachCurative effects
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 145-146,149 )