Analysis of risk factors related to rupture of small (diameter≤5 mm) posterior communicating artery aneurysms
ZHANG Ying
JING Lin-kai
ZHANG Qian-qian
LIU Jian
ZHANG Yi-Sen
WANG Kun
MU Shi-Qing
YANG Xin-Jian
Abstract：Objective To analyze risk factors related to the rupture of small (diameter≤5 mm) posterior communicating artery (PCoA) aneurysms. Methods Eighty-three consecutive patients with small PCoA aneurysms, of whom, 47 had ruptured aneurysms and 36 unruptured, were retrospectively collected. The risk factors possibly related to the rupture of small PCoA aneurysms including the patients' age, sex, individual and disease history, morphologic parameters derived from 3D-DSA images and hemodynamic parameters were analyzed by univariate analysis and multivariate logistic regression analysis. Results The univariate analysis showed that the factors related to the rupture of the aneurysms included the patients' age, five morphological factors (bifurcation type, irregular shape, size, aspect ratio and size ratio), and five hemodynamic factors (wall shear stress, oscillatory shear index, area under low wall shear stress, complex and unstable flow pattern). Stepwise multivariate logistic regression analysis showed that the independent possible risk factors related to the rupture of the aneurysms included bifurcation type (OR 3.368, P=0.030), irregular shape (OR 5.706, P=0.014) and lower wall shear stress (OR 0.053, P=0.012). Conclusion It is suggested that bifurcation type, irregular shape and lower wall shear stress were the risk factors of small PCoA aneurysm rupture.
Keywords：Intracranial aneurysmsPosterior communicating arteryRuptureRisk factorsHemodynamics
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 138-140 )