Application of thrombelastography to guiding perioperative treatment of patients with severe traumatic brain injury
Abstract：Objective To investigate the value of thrombelastography (TEG) to perioperative treatment in patients with severe traumatic brain injury (TBI). Methods Seventy-eight patients with TBI were divided into TEG group (n=39) and control group (n=39). TEG tests were performed at different perioperative stages and different kinds of blood products including plasma, platelets and so on were intravenously infused according to the TEG results in the TEG group. The blood products were perioperatively infused according to the traditional experiential therapy in the control group. The operative duration, volumes of bleeding, blood products transfusion, and drainage 6 and 24 hours after the operation, and cases of unplanned second operation were compared between both the groups. Results There was no difference in the operation duration between both the groups. The volumes of bleeding, blood products transfusion and drainage 6 and 24 hours after the operation were significantly more in the control group than those in the TGE group (P<0.01). There were 2 patients undergoing unplanned second operations in the control group and there was no patient undergoing unplanned second operation in the TEG group. Conclusions The coagulation function can be monitored and the volumes of the bleeding and blood products transfusion can decreased by TEG, and therefore it is of important value to the perioperative treatment in the patients with TBI.
Keywords：ThrombelastographyCoagulation functionPerioperative treatmentTraumatic brain injury
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 17-19 )