Clinical diagnosis and management of pituitary incidentalomas
LI Yun-jun
LI Wen-de
GAO Jin-bao
CHEN Li-hua
WEI Qun
XU Ru-xiang
Abstract：Objective To explore the methods to diagnose and treat the pituitary incidentalomas. Method The clinical data of 53 patients with pituitary incidentalomas found by MRI from January, 2008 to December, 2013 were analyzed retrospectively. Results Of these 53 patients, 41 had symptoms including headaches, dizziness, fainting, visual dysfunction, cerebral infarct and so on and 12 not. There were the mild endocrine disorders in 4 patients. The diameters of the lesions were less than 1.0 cm in 31 patients, between 1.0 and 1.5 centimeters in 13 and more than 1.5 cm in 9. The pathological examination showed that of 29 patients who underwent endonasal transsphenoidal surgery, 18 suffered from nonfunctioning pituitary adenomas, 2 from growth hormone pituitary adenomas, 3 from pituitary hyperplasia, 3 from Rathke cysts, 2 from pituitary cysts and 1 from prolactinoma. Of 49 patients followed up for more than 1 year, 29 undergoing the surgery did not suffer from the recurrence of the lesions, 18 had unchanged pituitary lesions and 2 who did not undergo surgery had enlargement of the pituitary lesions. Of 2 patients with enlarged lesions, 1 received surgical treatment and 1 was continuously observed. Conclusion MRI examination of the pituitary bodies should be performed in the patients with headaches. Surgery is recommended in the patients with pituitary incidentaomas which are more than 1.0 cm in diameters. The regular following up is recommended in the patients with nonsecreting pituitary incidentalomas which are less than 1.0 cm in diameters.
Keywords：Pituitary incidentalomasDiagnosisTranssphenoidal surgery
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 341-343 )