Analysis of factors related to postoperative recurrence of benign meningiomas

ZHU Fei; XIE Kui; RAO Min; HUANG Xin; WU Ming; JIN Wei-xing; ZHU Jiong-ming

doi:10.13798/j.issn.1009-153X.2015.02.008

Abstract：Objective To explore the factors related to the recurrence of benign intracranial meningiomas after the surgery. Methods The clinical data of 178 patients with benign intracranial meningiomas undergoing surgery from November, 1988 to November, 2009 in our hospital were analyzed retrospectively, including the operative, imaging and following up data. The univariate analysis and multivariate analysis were performed for understanding the factors related to the postoperative recurrence of the meningiomas. Results Of 178 patients with intracranial mengingiomas undergoing the surgery, 28 (15.7%) suffered from the tumor recurrence 5 years after the surgery and 150 not. The univariate analysis showed that the factors related to the mengingiomas recurrence included the extent of surgical resection, tumorous site, shape, size, border and histopathologic type, and the patients' gender (P<0.05). Multiariable logistic regression analysis showed that factors predicting the tumorous recurrence included the tumorous site, shape, boundary and histopathologic type and extent of surgical resection of the tumor. Conclusions It is suggested that the recurrence of ntracranial meningiomas may be related to the extent of surgical resection, tumorous site, shape, size, border and histopathologic type, peritomorous edema and gender, especially to the extent of the resection of the tumor and the tumorous histopathologic type.