Effect of transcranial direct current stimulation combined with seated Taijiquan Yunshou in different sequences on cerebral cortical activation in stroke patients with hemiplegia:a functional near-infrared spectroscopy study
XU Qi
ZHENG Dingzhao
NIU Zhenyuan
YANG Yaling
WEN Weiyou
XU Jingsheng
WU Longqiang
WU Fan
YAN Tiebin
Abstract：Objective To investigate the immediate effect of transcranial direct current stimulation(tDCS)combined with seated Tai-jiquan Yunshou training under different sequences on cerebral cortical activation in stroke patients with hemiple-gia.
Methods From September to December,2024,14 stroke inpatients with hemiplegia were enrolled from the Fifth Hospi-tal of Xiamen.Based on the routine medication and rehabilitation,the patients were randomly assigned to a spe-cific intervention sequence,receiving three interventions in a fixed order:tDCS followed by Yunshou(S-Y group),Yunshou followed by tDCS(Y-S group),and simultaneous tDCS and Yunshou(Sim group).Functional near-infrared spectroscopy was used to detect oxyhemoglobin(HbO₂)concentration in bilateral sensorimotor cor-tex,premotor and supplementary motor cortex,and prefrontal cortex before and after each intervention.
Results Three patients dropped out.In all the regions of interest,inter-group effects were significant in HbO₂ concentra-tions(F>3.697,P<0.05),and interaction effects were significant in some brain regions(F>3.276,P<0.05).Post-hoc test showed a general trend of Sim Group≥S-Y Group>Y-S Group(P<0.05),although some varia-tions existed across different brain regions.
Conclusion Both simultaneous intervention(tDCS and Yunshou)and tDCS followed by Yunshou are more effective on immediate activation of key motor-related cortices in stroke patients with hemiplegia than Yunshou followed by tDCS intervention.
Keywords：strokehemiplegiatranscranial direct current stimulationTaijiquanYunshoufunctional near-infrared spectroscopybrain-limb coordinated rehabilitation
Publication Date：2025-10-25
Online Publishing Date：2025-11-19(First online date of this platform, not the publication date of the document)
Pages：7( 1121-1127 )