Spatiotemporal effect and mechanism of the integrated traditional Chinese and Western medicine brain-limb co-ordinated rehabilitation
YAN Tiebin
XU Qi
Abstract：The theoretical framework of the integrated traditional Chinese medicine(TCM)and Western medicine brain-limb coor-dinated rehabilitation encompasses twelve intervention models,formed by combining four spatial combinations(brain-area Western medicine/TCM+upper/lower limb intervention of TCM/Western medicine)and three temporal sequences(brain-first,limb-first and simultaneous),exhibiting significant condition dependence(e.g.,types of disease,treatment course,baseline status)and population heterogeneity.Transcranial direct current stimulation combined with limb rehabil-itation can produce synergistic effects in some cases,but may also result in limited benefits or antagonistic effects.Cur-rently,there is a particular lack of clinical studies that systematically compare the effects of different temporal sequences(brain-first,limb-first,simultaneous).Functional near-infrared spectroscopy has been relatively maturely applied to re-veal the brain function regulation mechanisms underlying brain-limb coordinated rehabilitation.
Keywords：brain-limb coordinated rehabilitationintegrated traditional Chinese medicine and Western medicinetranscranial direct current stimulationspatiotemporal combinatorial effects
Publication Date：2025-10-25
Online Publishing Date：2025-11-19(First online date of this platform, not the publication date of the document)
Pages：4( 1117-1120 )